Brunekreef B
Department of Epidemiology and Public Health, University of Wageningen, The Netherlands.
Allergy. 1992 Oct;47(5):498-502. doi: 10.1111/j.1398-9995.1992.tb00672.x.
The relationship between home dampness and adult respiratory symptoms was investigated using data from a parent-administered questionnaire on childhood respiratory symptoms that also included questions on parental respiratory symptoms. Questionnaires were returned by the parents of 3344 children living in the town of Helmond, The Netherlands. The response was 73%. Home dampness was characterized by reports of damp stains or mould growth on indoor surfaces and was reported by 23.6% and 15.0% of the study population, respectively. Of the homes, 25.4% had dampness and/or mould. Information about respiratory symptoms was collected for the mothers and fathers of a population of 6-12-year-old schoolchildren. Symptoms analysed were cough, phlegm, wheeze, asthma, and allergy to pollen or house dust. Cough and phlegm in both men and women were found to be strongly associated with living in a damp home. Weaker associations were found for wheeze and asthma, and there was little association between living in a damp home and allergy to pollen or house dust. Current smoking was strongly associated with cough, phlegm and wheeze in both men and women. Smoking was inversely associated with allergy to pollen or house dust, suggesting that allergic subjects do not start smoking, or give up the habit. The results suggest that the association between home dampness and respiratory symptoms previously reported for children also applies to adults. Suggested mechanisms include exposure to biological contaminants produced by fungi or house dust mites, but it has not yet been documented to what extent these exposures are responsible.(ABSTRACT TRUNCATED AT 250 WORDS)
利用一份由家长填写的关于儿童呼吸道症状的问卷数据,对家庭潮湿与成人呼吸道症状之间的关系进行了调查,该问卷还包括有关父母呼吸道症状的问题。荷兰赫尔蒙德镇3344名儿童的家长返回了问卷。回复率为73%。家庭潮湿的特征是室内表面有潮湿污渍或霉菌生长报告,分别有23.6%和15.0%的研究人群报告有此类情况。在这些家庭中,25.4%存在潮湿和/或霉菌。收集了6至12岁学童群体中母亲和父亲的呼吸道症状信息。分析的症状包括咳嗽、咳痰、喘息、哮喘以及对花粉或屋尘的过敏。发现男性和女性的咳嗽和咳痰都与居住在潮湿的家中密切相关。喘息和哮喘的相关性较弱,居住在潮湿的家中与对花粉或屋尘的过敏之间几乎没有关联。当前吸烟与男性和女性的咳嗽、咳痰及喘息密切相关。吸烟与对花粉或屋尘的过敏呈负相关,这表明过敏者不开始吸烟或会戒掉吸烟习惯。结果表明,先前报道的儿童家庭潮湿与呼吸道症状之间的关联也适用于成年人。推测的机制包括接触由真菌或屋尘螨产生的生物污染物,但这些接触在多大程度上起作用尚未得到证实。(摘要截选于250词)