David J M, Ruaux C, Bachaud J M, Bonnet F, Lucot H, Boneu A, Suc E, Cabarrot E
Service de Chirurgie ORL et Cervico-Faciale, Centre Claudius Regaud, Toulouse.
Ann Otolaryngol Chir Cervicofac. 1992;109(4):183-7.
This study involved 38 patients with occult papillary carcinoma of the thyroid gland treated by total thyroidectomy and bilateral prophylactic neck dissection. The histological results show the glandular multicentricity on either side, both in single nodule (65%) and in multinodular goiter (73.3%). High risk of cervical spreading clearly appears in papillary carcinoma (18.4% of the patients) even in these small foci (lower than 10 mm). Topography of involvement brings into prominence two main territories: paratracheal, mid and lower jugularly nodes (involved in 92.8% of the positive dissections).
本研究纳入了38例经甲状腺全切除术和双侧预防性颈淋巴结清扫术治疗的甲状腺隐匿性乳头状癌患者。组织学结果显示双侧均存在腺体内多中心性，单结节（65%）和多结节性甲状腺肿（73.3%）中均如此。即使在这些微小病灶（小于10mm）中，乳头状癌患者也明显存在颈部转移的高风险（18.4%的患者）。受累部位的分布突出了两个主要区域：气管旁、颈中部和下部淋巴结（在92.8%的阳性清扫中受累）。
