Thömke F, Hopf H C
Department of Neurology, University of Mainz, Germany.
Brain. 1992 Dec;115 ( Pt 6):1901-10. doi: 10.1093/brain/115.6.1901.
Five patients with acquired monocular elevation paresis were investigated using direct current electroculography. With recovery, upward saccade velocities significantly increased in both eyes in all patients. The gain of upward-following eye movements significantly increased in the paretic eye of all patients and in the opposite eye of four patients. These findings are interpreted in terms of an asymmetric upgaze palsy which clinically presented as monocular elevation paresis in the more severely affected eye. A brainstem lesion contralateral to monocular elevation paresis was suggested in four patients by contralateral Horner's syndrome and contralateral abduction paresis, each in one patient, and contralateral ptosis in two patients. In only one patient, computerized tomography and magnetic resonance imaging substantiated a contralateral meso-diencephalic lesion.
对5例获得性单眼上睑提肌麻痹患者进行了直流电眼电图检查。随着恢复，所有患者双眼的向上扫视速度均显著增加。所有患者患眼以及4例患者对侧眼的向上跟随眼动增益均显著增加。这些发现被解释为不对称性上视麻痹，临床上表现为受累更严重的眼睛出现单眼上睑提肌麻痹。4例患者因对侧霍纳综合征、对侧外展麻痹（各1例）以及对侧上睑下垂（2例）提示单眼上睑提肌麻痹对侧存在脑干病变。仅1例患者的计算机断层扫描和磁共振成像证实了对侧中脑-间脑病变。
