The gene for leukocyte antigen-related tyrosine phosphatase (LAR) is localized to human chromosome 1p32, a region frequently deleted in tumors of neuroectodermal origin.
作者信息
Jirik F R, Harder K W, Melhado I G, Anderson L L, Duncan A M
机构信息
Biomedical Research Centre, University of British Columbia, Vancouver, Canada.
出版信息
Cytogenet Cell Genet. 1992;61(4):266-8. doi: 10.1159/000133418.
PMID:1486801
Abstract
In situ hybridization was employed to localize a cDNA probe from the human protein tyrosine phosphatase gene LAR to human metaphase chromosomes. LAR, a putative tumor suppressor gene, has been localized to 1p32, a chromosomal region that is frequently found deleted in human neuroblastoma and pheochromocytoma.
摘要
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