Pallotti Federica, Seregni Ettore, Ferrari Leonardo, Martinetti Antonia, Biancolini Donatella, Bombardieri Emilio
Nuclear Medicine Division, National Cancer Institute, Milan, Italy.
Tumori. 2003 Sep-Oct;89(5):547-9. doi: 10.1177/030089160308900519.
Postsurgical hypoparathyroidism is the most common cause of chronic hypocalcemia. This condition may occur after removal of all parathyroid glands or after interruption of the blood supply to the parathyroid glands during thyroidectomy and radical neck dissection. The severity of the clinical presentation of hypocalcemia may vary from an asymptomatic laboratory finding to a severe life-threatening condition. Persistent hypoparathyroidism requires treatment that must be maintained throughout the patient's lifetime, and for this reason care is required to avoid complications. In this review the most relevant aspects of calcium homeostasis and its alteration in hypoparathyroidism are briefly discussed. In addition, the main approaches to treatment of the hypocalcemic state are presented.
术后甲状旁腺功能减退是慢性低钙血症最常见的原因。这种情况可能发生在所有甲状旁腺被切除后，或在甲状腺切除术和根治性颈清扫术中甲状旁腺血液供应中断后。低钙血症临床表现的严重程度可能从无症状的实验室检查结果到严重的危及生命的情况不等。持续性甲状旁腺功能减退需要终身治疗，因此需要小心避免并发症。在这篇综述中，简要讨论了钙稳态及其在甲状旁腺功能减退中的改变的最相关方面。此外，还介绍了治疗低钙血症状态的主要方法。
