Nilsson K, Heimer G
Department of Obstetrics and Gynecology, Orebro, Sweden.
Gynecol Obstet Invest. 1992;34(4):234-6. doi: 10.1159/000292768.
In order to be able to evaluate the systemic influence of exogenous estrogen therapy in different conditions, it is important to have knowledge of the endogenous estrogen levels. The present study was undertaken to assess the basic levels and possible fluctuations of endogenous estrogen in postmenopausal women with urogenital estrogen deficiency. Plasma concentration levels of unconjugated estrone and estradiol were measured at regular intervals during 24 h in 5 postmenopausal women without estrogen treatment. All women had very low levels of estradiol. No diurnal fluctuation was found. Estrone levels were not measurable with a sensitive RIA technique.
为了能够评估外源性雌激素疗法在不同情况下的全身影响，了解内源性雌激素水平很重要。本研究旨在评估患有泌尿生殖系统雌激素缺乏的绝经后女性内源性雌激素的基础水平及可能的波动情况。在5名未接受雌激素治疗的绝经后女性中，于24小时内定期测量血浆中未结合雌酮和雌二醇的浓度水平。所有女性的雌二醇水平都非常低。未发现昼夜波动。采用灵敏的放射免疫分析技术无法检测到雌酮水平。
