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明尼苏达州罗切斯特市1990年至1994年额颞叶变性的发病率。

The incidence of frontotemporal lobar degeneration in Rochester, Minnesota, 1990 through 1994.

作者信息

Knopman D S, Petersen R C, Edland S D, Cha R H, Rocca W A

机构信息

Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

出版信息

Neurology. 2004 Feb 10;62(3):506-8. doi: 10.1212/01.wnl.0000106827.39764.7e.

Abstract

The records-linkage system of the Rochester Epidemiology Project was used to ascertain incident cases of frontotemporal lobar degeneration (FTLD) in Rochester, MN, from 1990 through 1994. Four cases of FTLD were identified (all women); two were confirmed neuropathologically. All were of the behavioral-dysexecutive type and had onset before age 70. The incidence rates (new cases per 100,000 person-years) were 2.2 for ages 40 to 49, 3.3 for ages 50 to 59, and 8.9 for ages 60 to 69. For comparison, the corresponding rates for Alzheimer disease were 0.0, 3.3, and 88.9.

摘要

罗切斯特流行病学项目的记录链接系统用于确定1990年至1994年明尼苏达州罗切斯特市额颞叶痴呆(FTLD)的发病病例。共识别出4例FTLD(均为女性);其中2例经神经病理学证实。所有病例均为行为-执行功能障碍型,发病年龄均在70岁之前。40至49岁年龄组的发病率(每10万人年的新发病例数)为2.2,50至59岁年龄组为3.3,60至69岁年龄组为8.9。作为对比,阿尔茨海默病相应年龄组的发病率分别为0.0、3.3和88.9。

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