Häkkinen Arja, Sokka Tuulikki, Hannonen Pekka
Central Finland Health Care District, Jyväskylä, Finland.
Arthritis Rheum. 2004 Feb 15;51(1):56-62. doi: 10.1002/art.20088.
To evaluate the impact of a 2-year home-based strength-training program on physical function in patients with early rheumatoid arthritis (RA) after a subsequent 3-year followup.
Seventy patients with early RA were randomized to perform either strength training (experimental group [EG]) or range-of-motion exercises (control group [CG]). Maximal strength values were recorded by dynamometers. The Modified Disease Activity Score (DAS28), pain, Health Assessment Questionnaire (HAQ), walking speed, and stair-climbing speed were also measured.
The maximum strength of assessed muscle groups increased by 19-59% in the EG during the training period and remained at the reached level throughout the subsequent 3 years. Muscle strength improved in the CG by 1-31%, but less compared with the EG. During the 2-year training period, DAS28 decreased by 50% and 45% and pain by 67% and 39% in the EG and CG, respectively. The differences in muscle strength, DAS28, and HAQ were significantly in favor of the EG both at the 2-year and 5-year followup assessments.
The improvements achieved during the 2-year strength-training period were sustained for 3 years in patients with early RA.
评估一项为期2年的居家力量训练计划对早期类风湿关节炎(RA)患者身体功能的影响,并进行为期3年的随访。
70例早期RA患者被随机分为两组,分别进行力量训练(实验组[EG])或关节活动度练习(对照组[CG])。使用测力计记录最大力量值。同时测量改良疾病活动评分(DAS28)、疼痛程度、健康评估问卷(HAQ)、步行速度和爬楼梯速度。
在训练期间,实验组评估肌肉群的最大力量增加了19%至59%,并在随后的3年中保持在该水平。对照组肌肉力量提高了1%至31%,但与实验组相比增幅较小。在为期2年的训练期间,实验组和对照组的DAS28分别下降了50%和45%,疼痛程度分别下降了67%和39%。在2年和5年的随访评估中,实验组在肌肉力量、DAS28和HAQ方面的差异均显著优于对照组。
早期RA患者在为期2年的力量训练期间所取得的改善在3年内得以持续。