Department of Physical Medicine and Rehabilitation, Izmir Bozyaka Training and Research Hospital, Bozyaka, 35380, Izmir, Turkey.
Rheumatol Int. 2011 Feb;31(2):171-6. doi: 10.1007/s00296-009-1242-7. Epub 2009 Nov 5.
We previously reported the efficacy of a 4-week home-based exercise therapy for patients with rheumatoid arthritis (RA). In this study, we aimed to investigate whether short-term improvements in the functional status and quality of life were maintained at 1 year. Patients who completed 4-week home-based exercise program were advised to maintain the same exercises for 1 year duration. Changes of functional status and quality of life in patients with RA were evaluated by the Health Assessment Questionnaire (HAQ) and the Rheumatoid Arthritis Quality of Life Scale (RAQoL). The change of the variables at the different time points (baseline, 4 weeks, and 1 year) was assessed by the repeated measure of ANOVA test with Geisser-Greenhouse correction. Pairwise ANOVA comparisons adjusted using the Bonferroni correction were conducted. Twenty-eight (63.6%) of 44 patients were available for follow-up at 1 year. The results of repeated measure ANOVA showed that there was a statistically significant difference between three assessments in the HAQ (P = 0.015) and RAQoL (P = 0.037) scores at the end of the follow-up. Improvements in the functional status and health-related quality of life at 4 weeks were maintained at 1-year follow-up. In conclusion, we observed significant improvements in the functional status and health-related quality of life by 4-week home-based exercise program. Furthermore, these improvements were maintained at 1-year follow-up. Further studies are needed to confirm the usefulness of the home-based exercise therapy.
我们之前报道了一项针对类风湿关节炎(RA)患者的为期 4 周的家庭基础运动疗法的疗效。在这项研究中,我们旨在探讨功能状态和生活质量的短期改善是否能在 1 年内得到维持。完成 4 周家庭基础运动方案的患者被建议在 1 年内保持相同的运动。通过健康评估问卷(HAQ)和类风湿关节炎生活质量量表(RAQoL)评估 RA 患者的功能状态和生活质量变化。使用重复测量方差分析(ANOVA)检验和 Geisser-Greenhouse 校正评估不同时间点(基线、4 周和 1 年)变量的变化。使用 Bonferroni 校正进行调整的成对 ANOVA 比较。44 例患者中有 28 例(63.6%)在 1 年后可进行随访。重复测量 ANOVA 的结果显示,在随访结束时,HAQ(P=0.015)和 RAQoL(P=0.037)评分的三次评估之间存在统计学差异。在 4 周时的功能状态和健康相关生活质量的改善在 1 年的随访中得到维持。总之,我们观察到 4 周家庭基础运动方案能显著改善功能状态和健康相关生活质量,且这些改善在 1 年的随访中得以维持。需要进一步的研究来证实家庭基础运动疗法的有效性。