Walsh J K, Engelhardt C L
Sleep Disorders and Research Center, Deaconess Hospital, St. Louis, Mo. 63139.
J Clin Psychiatry. 1992 Dec;53 Suppl:10-7; discussion 18.
Data from the National Disease and Therapeutic Index for the time period 1987-1991 (IMS, America) were examined for recent trends in the pharmacologic treatment of insomnia. All medications given with the desired action of promoting sleep or sedation at night were categorized as benzodiazepine hypnotics, benzodiazepine nonhypnotics, antidepressants, or other. From 1987 to 1991, the following trends were found: (1) overall pharmacologic treatment for insomnia decreased by approximately 10%, (2) use of benzodiazepine hypnotics fell about 30% during this time period, (3) use of antidepressants for insomnia increased by 100%, and (4) the noted changes were somewhat stronger for institutionalized patients than for ambulatory patients. These changes in the pharmacologic treatment of insomnia may be related to widespread media attention and are not supported by scientific data.
对美国IMS公司提供的1987 - 1991年国家疾病与治疗指数数据进行了分析，以研究失眠药物治疗的近期趋势。所有旨在促进夜间睡眠或镇静的药物被归类为苯二氮䓬类催眠药、苯二氮䓬类非催眠药、抗抑郁药或其他药物。1987年至1991年发现了以下趋势：（1）失眠的总体药物治疗减少了约10%，（2）在此期间苯二氮䓬类催眠药的使用量下降了约30%，（3）用于失眠治疗的抗抑郁药使用量增加了100%，（4）机构化患者的上述变化比门诊患者更为明显。失眠药物治疗的这些变化可能与媒体的广泛关注有关，且未得到科学数据的支持。
