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共病对失眠药物治疗处方的影响:来自1995 - 2004年美国国家门诊数据的证据

The influence of co-morbidities on prescribing pharmacotherapy for insomnia: evidence from US national outpatient data 1995-2004.

作者信息

Pawaskar Manjiri D, Joish Vijay N, Camacho Fabian T, Rasu Rafia S, Balkrishnan Rajesh

机构信息

Department of Pharmacy Practice and Administration, Ohio State University College of Pharmacy, Columbus, OH, USA.

出版信息

J Med Econ. 2008;11(1):41-56. doi: 10.3111/13696990701817491.

Abstract

OBJECTIVE

Patients with insomnia are likely to have other co-morbidities that could affect pharmacotherapeutic choices. This study examined the prevalence and impact of co-morbidities on the pharmacological treatment of insomnia.

STUDY DESIGN

A retrospective data analysis of the National Ambulatory Medical Care Survey from 1995 to 2004, comprising patients with a diagnosis of insomnia, was conducted. Multivariate logistic regression models were used to predict the impact of co-morbidities on pharmacotherapy for insomnia.

RESULTS

A total of 5,487 unweighted patient visits with insomnia were identified, representing 161.4 million patients in the US. Approximately 38% of these patients had at least one co-morbid condition. Patients with mental co-morbidities, especially anxiety, had decreased likelihood of receiving pharmacotherapy for insomnia.

CONCLUSIONS

Mental co-morbidities such as episodic mood disorder, anxiety and depression are prevalent in patients with insomnia. However, many co-morbid patients do not receive pharmacological therapy specific for insomnia.

摘要

目的

失眠患者可能伴有其他共病,这可能会影响药物治疗的选择。本研究调查了共病的患病率及其对失眠药物治疗的影响。

研究设计

对1995年至2004年美国国家门诊医疗调查中诊断为失眠的患者进行回顾性数据分析。采用多变量逻辑回归模型预测共病对失眠药物治疗的影响。

结果

共确定了5487例未加权的失眠患者就诊病例,代表美国1.614亿患者。其中约38%的患者至少有一种共病。伴有精神共病的患者,尤其是焦虑症患者,接受失眠药物治疗的可能性降低。

结论

发作性情绪障碍、焦虑和抑郁等精神共病在失眠患者中很常见。然而,许多共病患者未接受针对失眠的药物治疗。

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