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利用表面电位光谱特征解决神经电图中的逆问题。

Use of surface potential spectral characteristics for solving the inverse problem in electroneurography.

作者信息

Dimitrov G V, Lateva Z C, Dimitrova N A

机构信息

Bulgarian Academy of Science, CLBA, Sofia.

出版信息

Med Biol Eng Comput. 1992 Jul;30(4):399-405. doi: 10.1007/BF02446167.

DOI:10.1007/BF02446167
PMID:1487940
Abstract

The changes in the power spectra of single-fibre extracellular action potentials (SFEAPs) generated in an infinite anisotropic frequency-dependent volume conductor, which occurred as a result of alterations in the propagation velocity v and duration T(in) of the intracellular action potential (IAP) were analytically determined. Effects of the temporal and spatial dispersions of almost synchronously activated fibres on the power spectrum of compound extracellular potentials (CEPs) were analysed for different shapes and sizes of the activated fibres' territory. It was found that, as a result of desynchronisation in the fibres' activation, dips existed in the CEP power spectra and that the frequencies of the dips depended on the degree of desynchronisation but did not depend on the velocity. It was shown that the hypothetical power spectrum of compound IAP was sensitive to the variations in the desynchronisation in the fibres' activation and in the risetime and duration of IAP even at a great fibre electrode distance typical for surface recordings.

摘要

分析确定了在无限各向异性频率依赖性体积导体中产生的单纤维细胞外动作电位(SFEAP)功率谱的变化,这些变化是由于细胞内动作电位(IAP)的传播速度v和持续时间T(in)的改变而发生的。针对激活纤维区域的不同形状和大小,分析了几乎同步激活的纤维的时间和空间色散对复合细胞外电位(CEP)功率谱的影响。结果发现,由于纤维激活的不同步,CEP功率谱中存在凹陷,凹陷的频率取决于不同步的程度,但不取决于速度。结果表明,即使在表面记录典型的较大纤维电极距离下,复合IAP的假设功率谱对纤维激活不同步以及IAP上升时间和持续时间的变化也很敏感。

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