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Malignant thyroid tumors occurring in the mouse after prolonged hormonal imbalance during the ingestion of thiouracil.

作者信息

MORRIS H P, DALTON A J, GREEN C D

出版信息

J Clin Endocrinol Metab. 1951 Nov;11(11):1281-95. doi: 10.1210/jcem-11-11-1281.

DOI:10.1210/jcem-11-11-1281
PMID:14880608
Abstract
摘要

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1
Malignant thyroid tumors occurring in the mouse after prolonged hormonal imbalance during the ingestion of thiouracil.在摄入硫脲期间长期激素失衡后小鼠体内发生的恶性甲状腺肿瘤。
J Clin Endocrinol Metab. 1951 Nov;11(11):1281-95. doi: 10.1210/jcem-11-11-1281.
2
[Problem of the significance of thiouracil derivatives for the development of malignant tumors, especially of the thyroid gland].[硫脲嘧啶衍生物对恶性肿瘤尤其是甲状腺肿瘤发生发展的意义问题]
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3
The role of thiouracil in the induction, growth, and transplantability of mouse thyroid tumors.硫脲嘧啶在小鼠甲状腺肿瘤的诱导、生长及可移植性方面的作用。
Science. 1951 Jul 13;114(2950):44-6. doi: 10.1126/science.114.2950.44.
4
Age and diet effect on thyroid-serum ratio, PBI, and thyroidal iodine and histology in rodents.年龄和饮食对啮齿动物甲状腺-血清比率、蛋白结合碘、甲状腺碘及组织学的影响。
Am J Physiol. 1962 Feb;202:325-8. doi: 10.1152/ajplegacy.1962.202.2.325.
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THE EFFECT OF NUTRITIONAL STATUS AND THYROID FUNCTION ON THE METABOLISM OF OESTRADIOL.营养状况和甲状腺功能对雌二醇代谢的影响。
J Endocrinol. 1965 Apr;32:107-15. doi: 10.1677/joe.0.0320107.
6
Effect of iodide and thyroid on the production of tumors of the thyroid and pituitary by propylthiouracil.碘化物和甲状腺对丙硫氧嘧啶所致甲状腺及垂体肿瘤生成的影响。
Endocrinology. 1953 Feb;52(2):188-203. doi: 10.1210/endo-52-2-188.
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Influence of variation in environmental temperature and thyroid status on growth and feed consumption of the male mouse.环境温度变化和甲状腺状态对雄性小鼠生长及采食量的影响
Am J Physiol. 1950 Feb;160(2):253-8. doi: 10.1152/ajplegacy.1950.160.2.253.
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Carcinoma of the thyroid occurring in a case of diffuse toxic hyperplasia treated preoperatively with thiouracil.甲状腺癌发生于1例术前用硫脲嘧啶治疗的弥漫性毒性增生患者。
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A case of solitary toxic adenoma of the thyroid in an adult with an evaluation of the pre- and postoperative use of thiouracil in thyrotoxicosis.一例成人甲状腺孤立性毒性腺瘤病例，并对甲状腺毒症患者术前和术后使用硫脲类药物的情况进行评估。
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[Morphological features of experimental tumors of the thyroid gland induced in rats by 6-methylthiouracil].[6-甲基硫氧嘧啶诱发大鼠甲状腺实验性肿瘤的形态学特征]
Vopr Onkol. 1959;5:578-92.

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动物癌症模型中关于永生性和自主性的证据常常未被提供，这在癌症生物学的关键问题上造成了混乱。
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Spontaneous Cancers, But Not Many Induced Ones in Animals, Resemble Semi-New Organisms that Possess a Unique Programmed Cell Death Mode Different from Apoptosis, Senescent Death, Necrosis and Stress-Induced Cell Death.自发癌症，而非动物中的许多诱导性癌症，类似于半新生物体，其拥有一种不同于凋亡、衰老死亡、坏死和应激诱导细胞死亡的独特程序性细胞死亡模式。
J Cancer. 2018 Nov 25;9(24):4726-4735. doi: 10.7150/jca.26502. eCollection 2018.
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[Histopathology & therapy of hyperthyroidism of wild rabbit caused by fright].[惊吓所致野兔甲状腺功能亢进的组织病理学与治疗]
Virchows Arch Pathol Anat Physiol Klin Med. 1952 Feb;321(3):238-74. doi: 10.1007/BF01886798.
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The dependency of thyroid cancer; a review.甲状腺癌的相关性；综述
Ann Surg. 1957 Dec;146(6):879-91. doi: 10.1097/00000658-195712000-00001.
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Recent progress in cancer research.癌症研究的最新进展。
Public Health Rep (1896). 1953 Mar;68(3):309-16.