O'Carroll R E, Moffoot A, Ebmeier K P, Goodwin G M
MRC Brain Metabolism Unit, Royal Edinburgh Hospital.
Psychol Med. 1992 Nov;22(4):903-9. doi: 10.1017/s0033291700038472.
The National Adult Reading Test (NART) is widely used in clinical and research settings to estimate pre-morbid intellectual levels. The validity of the NART in estimating premorbid ability in Alcoholic Korsakoff Syndrome (AKS) is examined in the present study. Twenty AKS subjects were compared with 40 healthy controls. The validity of the NART as a pre-morbid measure in AKS was examined using four methods. AKS subjects made more NART errors than controls, had lower NART predicted IQ than demographically predicted IQ, made more NART errors than predicted by demographic variables and demonstrated NART performance which correlated with degree of memory impairment. It is concluded that NART performance is detrimentally affected by the AKS and that estimating pre-morbid intellectual level in Korsakoff's psychosis using the NART may be invalid. Furthermore, it is postulated that the impaired ability to pronounce correctly irregular words in AKS may reflect a failure in cognitive 'error checking' which may represent a consequence of frontal lobe dysfunction.
国家成人阅读测验（NART）在临床和研究环境中被广泛用于评估病前智力水平。本研究考察了NART在评估酒精性柯萨科夫综合征（AKS）病前能力方面的有效性。将20名AKS受试者与40名健康对照者进行比较。使用四种方法检验了NART作为AKS病前测量方法的有效性。AKS受试者的NART错误比对照组更多，NART预测智商低于人口统计学预测智商，NART错误比人口统计学变量预测的更多，并且NART表现与记忆损害程度相关。得出的结论是，AKS对NART表现有不利影响，使用NART评估柯萨科夫精神病的病前智力水平可能无效。此外，据推测，AKS中正确发音不规则单词的能力受损可能反映了认知“错误检查”的失败，这可能是额叶功能障碍的结果。
