al-Sulaiman M H, Mousa D H, Dhar J M, al-Khader A A
Department of Nephrology, Riyadh Armed Forces Hospital, Saudi Arabia.
Am J Nephrol. 1992;12(5):384-6. doi: 10.1159/000168478.
We report a patient who developed generalized Kaposi's sarcoma (extensive skin and stomach lesions) 24 months after renal transplantation whilst on cyclosporin (CyA) and prednisolone. Kaposi's sarcoma disappeared completely upon withdrawal of CyA. The patient remained with a well-functioning graft and free of Kaposi's sarcoma for 36 months on prednisolone alone. CyA was reintroduced following an episode of acute rejection. Within 8 weeks, Kaposi's sarcoma reappeared on the skin at the same sites as the previously healed lesions. They completely disappeared again upon withdrawal of CyA. Azathioprine was then introduced and Kaposi's sarcoma lesions reappeared 6 months later.
我们报告了一名肾移植患者，该患者在接受环孢素（CyA）和泼尼松龙治疗24个月后发生了全身性卡波西肉瘤（广泛的皮肤和胃部病变）。停用CyA后，卡波西肉瘤完全消失。该患者仅使用泼尼松龙，移植肾功能良好且无卡波西肉瘤达36个月。在一次急性排斥反应发作后重新使用了CyA。在8周内，卡波西肉瘤在先前愈合病变的相同部位再次出现在皮肤上。停用CyA后它们又完全消失了。然后引入硫唑嘌呤，6个月后卡波西肉瘤病变再次出现。
