Izu R, Gardeazabal J, González M, Landa N, Ratón J A, Díaz-Pérez J L
Department of Dermatology, Hospital de Cruces, Bilbao, Spain.
Photodermatol Photoimmunol Photomed. 1992 Apr;9(2):86-8.
Enoxacin is a second-generation quinolone derivative recently introduced in Spain. Its activity comes through the inhibition of bacterial DNA-gyrase and it has a good antibacterial capacity against a broad spectrum of gram-positive and gram-negative bacteria. It is presumed to be less toxic than the rest of the quinolones and its use is increasing, specially to treat infections of the urogenital tract. Cases of photosensitivity to enoxacin have been very rarely reported. We describe 2 patients with photosensitivity reactions due to this drug.
依诺沙星是一种最近在西班牙上市的第二代喹诺酮衍生物。它通过抑制细菌DNA回旋酶发挥作用，对多种革兰氏阳性菌和革兰氏阴性菌具有良好的抗菌能力。据推测，它的毒性低于其他喹诺酮类药物，其应用正在增加，特别是用于治疗泌尿生殖道感染。依诺沙星引起光敏反应的病例报道极少。我们描述了2例因该药物引起光敏反应的患者。
