[精神分裂症中的额叶低活动：视角的转变]
[Frontal lobe hypoactivity in schizophrenia: change in perspective].
作者信息
Laplante L, Everett J
机构信息
Université Laval, Ecole de Psychologie, Sainte-Foy, Québec, Canada.
出版信息
J Psychiatry Neurosci. 1992 Nov;17(5):199-205.
Abstract
Many attempts to isolate a dysfunctional site in the brain of schizophrenic patients have converged in a neuropathological conception of the disease based on frontal lobe hypoactivity. Recent data from studies using cytoarchitectony, computerized tomographic scans, cerebral regional blood flow, smooth pursuit eye movements and neuropsychological assessments are discussed. Current data on the hypofrontality hypothesis in schizophrenia seem to suggest an associationist rather than a localisationist perspective of the disorder.
摘要
许多试图在精神分裂症患者大脑中分离出功能失调部位的尝试，都汇聚成了一种基于额叶活动减退的疾病神经病理学概念。本文讨论了近期使用细胞构筑学、计算机断层扫描、脑区局部血流、平稳跟踪眼球运动和神经心理学评估等研究得出的数据。目前关于精神分裂症前额叶功能减退假说的数据似乎表明，该疾病的观点是联想主义而非定位主义的。
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[Frontal lobe hypoactivity in schizophrenia: change in perspective].[精神分裂症中的额叶低活动：视角的转变]
J Psychiatry Neurosci. 1992 Nov;17(5):199-205.
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