Usera M A, Aladueña A, Jaime M L, Raya C, Fuster C, Planes A, Bartolomé R M
Sección de Enterobacterias, Instituto de Salud Carlos III, Majadahonda, Madrid.
Enferm Infecc Microbiol Clin. 1992 Nov;10(9):539-42.
Most Salmonella typhi isolated in Spain are susceptible to antibiotics commonly used in its treatment as chloramphenicol, ampicillin and cotrimoxazole. Three multiresistant strains have been isolated from different patients the last two years. Two phage type M1, biotype xylose tetrationate + strains were isolated from blood of two patients in Bembibre (León). One phage type E1a biotype xylose + tetrationate reductase + strain was isolated from blood and faeces of one patient in Barcelona. All strains harboured a 79 Mdal plasmid responsible for multiresistance, chloramphenicol acetyl transferase production and conjugative.
在西班牙分离出的大多数伤寒沙门氏菌对其治疗中常用的抗生素如氯霉素、氨苄青霉素和复方新诺明敏感。在过去两年中，已从不同患者身上分离出三株多重耐药菌株。从本比布雷（莱昂）两名患者的血液中分离出两株噬菌体M1型、木糖四酸盐利用型+生物型菌株。从巴塞罗那一名患者的血液和粪便中分离出一株噬菌体E1a型、木糖利用型+四酸盐还原酶利用型菌株。所有菌株都携带一个79兆道尔顿的质粒，该质粒负责多重耐药性、氯霉素乙酰转移酶的产生以及接合转移。
