NORTHROP J H
J Gen Physiol. 1952 Jan;35(3):471-81. doi: 10.1085/jgp.35.3.471.
B. megatherium cells were grown in various culture media, centrifuged and washed, and suspended in other culture media containing "C" or "T" phage. The per cent of infection, rate of growth, lysis, and phage production were determined. The behavior of the system depends on the culture medium in which the cells were grown and also on the culture medium in which they were mixed with phage. With the T phage it is possible to set up systems which yield the following results: 1. No infection, normal growth, no phage production. 2. Infection, normal growth, no lysis) phage production. 3. Infection, growth for several hours, lysis, and phage production. 4. Infection, no growth, lysis, and phage production. The C phage system is less affected by changes in the culture medium. The change in the behavior of the cells with T phage probably is not due to selection since it occurs without much growth of the culture, and is readily reversible.
巨大芽孢杆菌细胞在各种培养基中培养，经离心和洗涤后，悬浮于含有“C”或“T”噬菌体的其他培养基中。测定感染百分比、生长速率、裂解和噬菌体产生情况。该系统的行为取决于细胞生长所用的培养基，也取决于它们与噬菌体混合时所用的培养基。对于T噬菌体，可以建立能产生以下结果的系统：1. 无感染，正常生长，无噬菌体产生。2. 感染，正常生长，无裂解，有噬菌体产生。3. 感染，生长数小时，裂解，有噬菌体产生。4. 感染，无生长，裂解，有噬菌体产生。C噬菌体系统受培养基变化的影响较小。细胞与T噬菌体相互作用时行为的变化可能不是由于选择，因为这种变化在培养物生长不多的情况下就会发生，而且很容易逆转。
