Hacham-Zadeh S, Even-Paz Z
Clin Genet. 1978 May;13(5):404-8. doi: 10.1111/j.1399-0004.1978.tb04138.x.
A Jewish family, originating from Kurdistan and presenting erythrokeratodermia variabilis in three consecutive generations, is described. The major features were the variable age of onset (from early infancy to 6 years) and the distinctive cutaneous lesions with demarcated erythematous hyperkeratotic plaques with irregular borders. The affected members had mild to severe expressions of the disease. The skin lesions were not influenced by puberty, pregnancy or old age. None of the patients had lesions of the palms and soles or abnormal neurological signs.
本文描述了一个来自库尔德斯坦的犹太家庭，该家庭连续三代出现可变型红斑角化病。主要特征为发病年龄可变（从婴儿早期到6岁），以及具有边界不规则的界限性红斑角化性斑块的独特皮肤损害。受累成员有轻度至重度的疾病表现。皮肤损害不受青春期、妊娠或老年的影响。所有患者均无掌跖损害或异常神经体征。
