增生性玻璃体视网膜病变中的弹力纤维
Oxytalan fibres in proliferative vitreoretinopathy.
作者信息
Alexander R A, Hiscott P, McGalliard J, Grierson I
机构信息
Department of Pathology, Institute of Ophthalmology, London, United Kingdom.
出版信息
Ger J Ophthalmol. 1992;1(6):382-7.
The distribution of elastic and related fibres was studied in 29 fibrocellular membranes associated with proliferative vitreoretinopathy using histochemical, immunohistochemical and ultrastructural techniques. Ten subretinal and ten epiretinal membranes were subjected to light microscopical investigation, whilst the remaining nine membranes were examined by transmission electron microscopy. Oxytalan fibres, an elastic fibre precursor that is found in a variety of normal and pathological connective-tissue matrices, were identified in all of the specimens. Mature elastic fibres were not observed in any of the 29 membranes. The demonstration that oxytalan connective-tissue fibres contribute to the infrastructure of PVR membranes adds further evidence to the suggestion that this proliferative tissue might be the result of a repair mechanism.
利用组织化学、免疫组织化学和超微结构技术，对29例与增殖性玻璃体视网膜病变相关的纤维细胞性膜中的弹性纤维及相关纤维分布进行了研究。对10例视网膜下膜和10例视网膜前膜进行了光学显微镜检查，其余9例膜则通过透射电子显微镜进行检查。在所有标本中均鉴定出了Oxytalan纤维，它是一种存在于多种正常和病理结缔组织基质中的弹性纤维前体。在29例膜中均未观察到成熟的弹性纤维。Oxytalan结缔组织纤维对增殖性玻璃体视网膜病变膜的结构有贡献，这一发现进一步证明了这种增殖性组织可能是一种修复机制的结果。
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