圆锥角膜中结缔组织纤维的生成
Connective tissue fibre production in keratoconus.
作者信息
Jefferies L W, Alexander R A
机构信息
Department of Pathology, Institute of Ophthalmology, London, England, UK.
出版信息
Br J Biomed Sci. 1995 Mar;52(1):14-8.
In a histochemical and electron microscopic study of 45 cases of keratoconus, oxytalan fibres, a member of the elastic fibre family, were found in the extracellular tissues of the cornea. Oxytalan fibres were identified beneath the epithelium over the thinned central region of the conical cornea as well as in areas of stromal scarring. In a number of instances the apparently thickened Descemet's membrane was shown to include an oxytalan-containing retro-corneal layer. Oxytalan fibres were found to be immunostained by antibodies raised against collagen type VI.
在一项对45例圆锥角膜病例的组织化学和电子显微镜研究中，在角膜的细胞外组织中发现了弹力纤维家族成员氧化弹性纤维。在圆锥角膜变薄的中央区域上皮下方以及基质瘢痕形成区域均发现了氧化弹性纤维。在许多情况下，明显增厚的后弹力层显示包含一个含氧化弹性纤维的角膜后层。发现氧化弹性纤维可被抗VI型胶原抗体免疫染色。
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