通过区带离心法制备的大鼠肝细胞组分中HCO-3-ATP酶活性分布
HCO-3-ATPase activity distribution in rat liver cell fractions prepared by zonal centrifugation.
作者信息
Izutsu K T, Siegel I A, Smuckler E A
出版信息
Experientia. 1978 Jun 15;34(6):731-3. doi: 10.1007/BF01947288.
PMID:149017
Abstract
Plasma membrane sheets prepared by zonal centrifugation of a premicrosomal pellet obtained from a rat liver homogenate are devoid of HCO-3-ATPase activity. Since the microsomal fraction is also lacking in this ATPase activity, it can be concluded that the HCO-3-ATPase is not involved in the secretion of HCO-3 into bile.
摘要
通过对大鼠肝脏匀浆所得的微粒体前体沉淀进行区带离心制备的质膜片层缺乏HCO₃⁻ -ATP酶活性。由于微粒体部分也缺乏这种ATP酶活性，因此可以得出结论，HCO₃⁻ -ATP酶不参与HCO₃⁻分泌到胆汁中。
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