Iritani N, Wells W W
Biochim Biophys Acta. 1976 Jul 15;436(4):863-8. doi: 10.1016/0005-2736(76)90413-2.
Crude subcellular fractions from rat uterus contain a HCO-3 -stimulated Mg2+ -ATPase with properties analogous to those previously reported for the enzyme in gastric mucosa, pancreas, salivary gland and liver lyosome. Estradiol-17 beta treatment of ovariectomized rats resulted in an increase in uterine mitochondrial (HCO-3 +Mg2+)-ATPase and Mg2+ -ATPase activity. In an early response (105 min) to estradiol-17 beta treatment of ovariectomized rats, the lysosomal enzyme, beta-N-acetylglucosaminidase increased in the nuclear and mitochondrial fractions and decreased in the microsomal and supernatant fractions.
来自大鼠子宫的粗亚细胞组分含有一种受HCO₃⁻刺激的Mg²⁺-ATP酶，其特性与先前报道的胃黏膜、胰腺、唾液腺和肝溶酶体中的该酶类似。用17β-雌二醇处理去卵巢大鼠会导致子宫线粒体（HCO₃⁺+Mg²⁺）-ATP酶和Mg²⁺-ATP酶活性增加。在对去卵巢大鼠进行17β-雌二醇处理的早期反应（105分钟）中，溶酶体酶β-N-乙酰氨基葡萄糖苷酶在核和线粒体组分中增加，而在微粒体和上清液组分中减少。
