Chang T S, Hooper P L, Gonder J R, Shum D
Department of Ophthalmology, Victoria Hospital, London, Ont.
Can J Ophthalmol. 1992 Dec;27(7):326-30.
To assess the ability of trans-scleral application of the continuous-wave neodymium: YAG laser to produce retinal ablation with reproducible chorioretinal scars, retinal photocoagulation with the YAG laser was done in four Dutch-belted rabbits (eight eyes). Sharply defined, reproducible lesions were produced that were identical to those found following conventional treatment with the argon laser. At 0.2 J there was destruction of the outer retinal layers with sparing of the inner retinal layers. At 3.0 J full-thickness retinal reorganization was noted; however, even at this energy setting there was minimal histologic evidence of scleral damage. Focused laser energy produced distinctly more retinal destruction and obliteration of the retinal pigment epithelium than unfocused energy. The results suggest that trans-scleral photocoagulation with the YAG laser may be possible and would be particularly applicable in situations in which media opacities preclude visualization of the retina.
钇铝石榴石激光产生具有可重复性脉络膜视网膜瘢痕的视网膜消融能力，对4只荷兰带兔（8只眼）进行了钇铝石榴石激光视网膜光凝。产生了边界清晰、可重复的病变，这些病变与氩激光传统治疗后发现的病变相同。在0.2焦耳时，外层视网膜层被破坏，内层视网膜层未受影响。在3.0焦耳时，观察到全层视网膜重塑；然而，即使在这个能量设置下，巩膜损伤的组织学证据也很少。聚焦激光能量比未聚焦能量产生的视网膜破坏和视网膜色素上皮闭塞明显更多。结果表明，用钇铝石榴石激光进行经巩膜光凝可能可行，尤其适用于因介质混浊而无法观察视网膜的情况。
