Skvaril F, Gozze I
Int Arch Allergy Appl Immunol. 1978;57(4):315-8.
Plasmin-treated human gamma-globulin, isolated plasmin residual portion (PRG), Fab and Fc fragments were tested for anticomplementary properties. The plasmin digest had very low anticomplementary activity while some of its components were anticomplementary, the latter probably due to alterations resulting from the isolation procedures employed. The highest activity was found in the isolated Fc fragment, no activity being detected in the isolated Fab fragment. Various mixtures of the isolated components were also tested, the results indicating that the increase in anticomplementary activity of the PRG and the Fc fragment was markedly lower when the Fab fragment was present.
对经纤溶酶处理的人γ-球蛋白、分离出的纤溶酶残余部分（PRG）、Fab片段和Fc片段进行了抗补体特性测试。纤溶酶消化产物的抗补体活性非常低，而其某些成分具有抗补体活性，后者可能是由于所采用的分离程序导致的改变。在分离出的Fc片段中发现了最高活性，而在分离出的Fab片段中未检测到活性。还测试了分离成分的各种混合物，结果表明，当存在Fab片段时，PRG和Fc片段的抗补体活性增加明显较低。
