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局限性基底细胞样毛囊错构瘤

Localized basaloid follicular hamartoma.

作者信息

Kato N, Ueno H, Nakamura J

机构信息

Department of Dermatology, Otaru City General Hospital, Japan.

出版信息

J Dermatol. 1992 Oct;19(10):614-7. doi: 10.1111/j.1346-8138.1992.tb03739.x.

DOI:10.1111/j.1346-8138.1992.tb03739.x
PMID:1491090
Abstract

We report a 39-year-old Japanese woman with a 30 x 10 mm, skin-colored, soft, hairless, irregularly elevated plaque in the left retroauricular area. Histologically, it consistently showed features of atypical hair follicles; some showed immaturely developed basaloid epithelial islands invaginated with condensed stromal cells, and others were replaced or associated with solid strands, branching cords, or lace-like networks of undifferentiated basaloid cells. Although the clinical appearance of a typical localized basaloid follicular hamartoma is a plaque of alopecia, this case seems to be a variant, because the histological findings are so characteristic of the entity. The relationship of basaloid follicular hamartoma to other hair-follicle derived tumors is also considered.

摘要

我们报告了一名39岁的日本女性,其左耳后区域有一个30×10毫米、肤色、柔软、无毛、不规则隆起的斑块。组织学上,它始终显示出非典型毛囊的特征;一些显示出未成熟发育的基底样上皮岛,伴有浓缩的基质细胞内陷,另一些则被未分化的基底样细胞的实性条索、分支索或花边样网络所取代或与其相关。尽管典型的局限性基底样毛囊错构瘤的临床表现是脱发斑块,但该病例似乎是一种变体,因为组织学表现具有该实体的特征性。还考虑了基底样毛囊错构瘤与其他毛囊源性肿瘤的关系。

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