Pipicelli G, Pentimone F, Frustaci G, Notarangelo R, Beghè F
Divisione di Medicina Interna, Ospedale di Soverato, Catanzaro.
Minerva Med. 1992 Dec;83(12):819-25.
The Authors examine the relationship between diabetes mellitus, lipid metabolism and atherosclerosis with particular emphasis on the role of insulin and on the therapeutic consequences. The results of a study on the efficacy and tolerability of simvastatin in the treatment of hypercholesterolemia in non insulin-dependent diabetic patients are reported. Simvastatin administration induce a significant reduction and increase in total and HDL cholesterol levels respectively contributes to the decrease of triglycerides without interfering with the metabolic control of diabetic condition.
作者研究了糖尿病、脂质代谢与动脉粥样硬化之间的关系，特别强调了胰岛素的作用以及治疗后果。报告了一项关于辛伐他汀治疗非胰岛素依赖型糖尿病患者高胆固醇血症的疗效和耐受性的研究结果。服用辛伐他汀可分别使总胆固醇和高密度脂蛋白胆固醇水平显著降低和升高，有助于降低甘油三酯，且不干扰糖尿病病情的代谢控制。
