Chakraverty S C, Rafferty P R
Knightswood Hospital, Glasgow.
Scott Med J. 1992 Oct;37(5):141-3. doi: 10.1177/003693309203700504.
Endobronchial laser therapy has been performed at Knightswood Hospital, Glasgow since 1983. During the period 1983 to 1990, 62 patients underwent a total of 149 laser treatments. The principal indications for therapy were tracheo-carinal stridor (24%), dyspnoea due to bronchial occlusion (60%) and haemoptysis (13%). Squamous carcinoma accounted for 80% of the lesions. Over 75% of patients had already received some form of prior therapy (radiotherapy 71%, chemotherapy 8%, surgical resection 11%). Laser therapy reduced stridor in 67% of patients with tracheal and carinal tumours and produced symptomatic improvement in 72% of patients with bronchial obstruction but without evidence of lobar collapse. Haemoptysis was controlled in all but one of patients treated. Two patients (3.2%) died during laser treatment following severe haemorrhage.
自1983年起,格拉斯哥奈茨伍德医院就开展了支气管内激光治疗。在1983年至1990年期间,62例患者共接受了149次激光治疗。治疗的主要适应证为气管隆突部喘鸣(24%)、支气管阻塞所致呼吸困难(60%)和咯血(13%)。鳞状细胞癌占病变的80%。超过75%的患者已经接受过某种形式的前期治疗(放疗71%、化疗8%、手术切除11%)。激光治疗使67%的气管和隆突部肿瘤患者的喘鸣减轻,72%的支气管阻塞患者症状改善,但无肺叶萎陷的证据。除1例患者外,所有接受治疗的患者咯血均得到控制。2例患者(3.2%)在激光治疗期间因严重出血死亡。