Hetzel M R, Nixon C, Edmondstone W M, Mitchell D M, Millard F J, Nanson E M, Woodcock A A, Bridges C E, Humberstone A M
Thorax. 1985 May;40(5):341-5. doi: 10.1136/thx.40.5.341.
One hundred patients with tracheobronchial tumours were treated with the neodymium YAG (yttrium-aluminium-garnet) or argon laser for symptoms of airways obstruction caused by tumour (59 cases), complete collapse of a lung (17 cases), or recurrent haemoptysis (24 cases). Seventy four of them had relapsed or failed to respond to radiotherapy or chemotherapy and all were inoperable. Objective improvement in results of lung function tests or haemoptysis diary charts was seen in 37 patients with airways obstruction (63%), five (29%) with collapsed lung, and 14 (58%) with haemoptysis. Overall, 68 patients had symptomatic benefit and there was objective improvement in 56. Two deaths occurred in 288 treatment sessions both occurring as a result of asphyxia from minor haemorrhage in patients with advanced cylindromas and critical narrowing of the trachea or single remaining bronchus. In suitable patients with intraluminal tumour laser phototherapy is a valuable addition to conventional treatment.
100例气管支气管肿瘤患者因肿瘤导致气道梗阻症状(59例)、肺完全萎陷(17例)或反复咯血(24例),接受了钕钇铝石榴石(Nd:YAG)激光或氩激光治疗。其中74例曾接受放疗或化疗后复发或无效,均无法手术。37例气道梗阻患者(63%)、5例肺萎陷患者(29%)和14例咯血患者(58%)的肺功能测试结果或咯血日记图表有客观改善。总体而言,68例患者有症状改善,56例有客观改善。288次治疗中有2例死亡,均因晚期圆柱瘤患者轻微出血窒息,伴有气管或仅存单支支气管严重狭窄。对于合适的腔内肿瘤患者,激光光疗是传统治疗的一项有价值的补充。