Hetzel M R, Millard F J, Ayesh R, Bridges C E, Nanson E M, Swain C P, Williams I P
Br Med J (Clin Res Ed). 1983 Jan 1;286(6358):12-6. doi: 10.1136/bmj.286.6358.12.
Laser treatment in carcinoma of the bronchus is essentially palliative and is suitable for only a few patients. Patients selected for laser treatment must have predominantly endobronchial growth with normal bronchial anatomy still identifiable and symptoms due to the obstruction or to haemoptysis. A total of 34 patients with carcinoma of the bronchus were treated with argon gas or neodynium yttrium aluminium garnet crystal lasers. Good palliation was obtained in just over half the cases of partial obstruction of the trachea or main bronchus, but best results were obtained in lesions of the trachea or main carina. Re-expansion of the collapsed lung was achieved in some cases but with considerable risk of pneumonia. Haemoptysis was controlled at least partly in several cases. Laser treatment has the advantage of having no toxicity or dose limit and may be used in cases of poor respiratory function. The procedure was better tolerated than radiotherapy or chemotherapy and its relatively lower cost may justify setting up laser units in major cities.
支气管癌的激光治疗本质上是姑息性的，仅适用于少数患者。选择接受激光治疗的患者必须主要为支气管内生长，支气管解剖结构仍正常可辨，且有因阻塞或咯血引起的症状。共有34例支气管癌患者接受了氩气或钕钇铝石榴石晶体激光治疗。在气管或主支气管部分阻塞的病例中，略超过半数获得了良好的姑息效果，但气管或主隆突病变的治疗效果最佳。在一些病例中实现了萎陷肺的复张，但有相当大的肺炎风险。在几例病例中咯血至少得到了部分控制。激光治疗具有无毒性或剂量限制的优点，可用于呼吸功能差的病例。该治疗方法比放疗或化疗耐受性更好，其相对较低的成本可能证明在大城市设立激光治疗科室是合理的。
