Tobler H, Etter A, Müller F
Institute of Zoology, University of Fribourg, Switzerland.
Trends Genet. 1992 Dec;8(12):427-32. doi: 10.1016/0168-9525(92)90326-y.
Chromatin diminution in Parascaris and Ascaris represents the classical case of a developmentally programmed genome rearrangement. The process is very specific with respect to ontogenetic timing and chromosomal localization, and involves chromosomal breakage, new telomere formation and DNA degradation. Recent evidence from Ascaris lumbricoides var. suum suggests that chromatin diminution might have a function in gene regulation.
在副蛔虫和蛔虫中发生的染色质消减是发育程序控制的基因组重排的经典例子。该过程在个体发育时间和染色体定位方面非常特异，涉及染色体断裂、新端粒形成和DNA降解。来自猪蛔虫变种的最新证据表明，染色质消减可能在基因调控中具有作用。
