Diehl J F
Institut für Ernährungsphysiologie, Bundesforschungsanstalt für Ernährung, Karlsruhe.
Z Ernahrungswiss. 1992 Dec;31(4):225-45. doi: 10.1007/BF01610072.
In the 1950s to '70s, food additives and contaminants were considered important risk factors for cancer and other chronic diseases. Opinion leaders like F. Eichholtz and W. Kollath in Germany and R. Carson and J.J. Delaney in the United States maintained that the exclusion of man-made chemicals from the food supply would decisively contribute to better health. In contrast to these views, world-wide scientific opinion now emphasizes the role of personal lifestyle, e.g., over-nutrition, unbalanced diets, smoking, and excessive alcohol consumption in the causation of chronic diseases. Dietary guidelines now recommended for the prevention of cancer are largely identical with those recommended for the prevention of cardiovascular disease. Indications are that oxidative damage to DNA contributes importantly to both these diseases. In research the role of antioxidants and other protective substances in foods receives as much attention today as man-made carcinogens received in the past. Media reporting and nutrition counseling have taken very little notice of these fundamental changes in scientific opinion.
在20世纪50年代至70年代,食品添加剂和污染物被视为癌症及其他慢性病的重要风险因素。德国的F. 艾希霍尔茨和W. 科拉思以及美国的R. 卡森和J.J. 德莱尼等意见领袖坚持认为,将人造化学品排除在食品供应之外将对改善健康起到决定性作用。与这些观点形成对比的是,现在全球科学观点强调个人生活方式的作用,例如营养过剩、饮食不均衡、吸烟和过量饮酒在慢性病病因中的作用。目前推荐的预防癌症的饮食指南与预防心血管疾病的饮食指南基本相同。有迹象表明,DNA的氧化损伤对这两种疾病都有重要影响。在研究中,食品中抗氧化剂和其他保护物质的作用如今受到的关注与过去人造致癌物受到的关注一样多。媒体报道和营养咨询几乎没有注意到科学观点的这些根本变化。