Castro W H, Jerosch J, Halm H, Rondhuis J
Klinik und Poliklinik für Allgemeine Orthopädie, Westfälischen Wilhelms-Universität Münster.
Z Orthop Ihre Grenzgeb. 1992 Nov-Dec;130(6):467-71. doi: 10.1055/s-2008-1039654.
In an experimental study with standardized conditions nuclear material of 40 human lumbar discs was excised. In 20 the non-automated discectomy method was used (NAPLD-method). In the other 20 the automated discectomy method (APLD-method). The excised material was weighted. After the removal, the material of the NAPLD-method was wet with isotonic saline over 45 minutes and again weighted. Afterwards the wet material of both methods was freeze dried and again weighted. The weight of the wet material of the NAPLD-method in relation to that of the freeze dried material was a factor 11 (average value: 7.7 g in relation to 0.7 g) and in the APLD-method a factor 15 (average value: 4.5 g in relation to 0.3 g). This means, that the uptake and distribution of the saline is different in both methods and for this reason it is not allowed to compare the wet weight of the two methods. This has to be considered in clinical comparative studies. Because the biomechanical changes after a discectomy are dependent of the amount of the excised nuclear material, the NAPLD- and APLD-method can only be compared when the amount of the excised material is changed in a freeze dried weight.
在一项具有标准化条件的实验研究中，切除了40个人类腰椎间盘的核物质。其中20个采用非自动化椎间盘切除术方法（NAPLD法），另外20个采用自动化椎间盘切除术方法（APLD法）。对切除的物质进行称重。切除后，NAPLD法的物质用等渗盐水浸湿45分钟后再次称重。之后，两种方法的湿物质均进行冷冻干燥并再次称重。NAPLD法湿物质重量与冷冻干燥物质重量之比为11倍（平均值：7.7克相对于0.7克），APLD法为15倍（平均值：4.5克相对于0.3克）。这意味着，两种方法中盐水的吸收和分布不同，因此不允许比较两种方法的湿重。在临床比较研究中必须考虑这一点。由于椎间盘切除术后的生物力学变化取决于切除的核物质的量，只有当切除物质的量以冷冻干燥重量表示时，NAPLD法和APLD法才能进行比较。
