布鲁拉基因与11个绵羊血液多态性位点的遗传标记之间不存在连锁证据。

Absence of evidence for linkage between Booroola gene and genetic markers at 11 sheep blood polymorphic loci.

作者信息

Nguyen T C, Elsen J M, Cullen P R

机构信息

INRA-CRJ, Laboratoire des Groupes sanguins, Jouy-en-Josas, France.

出版信息

Anim Genet. 1992;23(6):525-7. doi: 10.1111/j.1365-2052.1992.tb00172.x.

DOI:10.1111/j.1365-2052.1992.tb00172.x

PMID:1492703

Abstract

Genetic linkage between the Booroola locus (Fec) and 11 sheep blood polymorphic loci (i.e. Tf, Hb, CA, OLA, and A, B, C, D, M, R, F41 red cell blood groups) was investigated in six large sire families (163 informative female offspring). The six sires tested were heterozygous for the Booroola allele (FecB) and for several genetic markers. No evidence in favour of linkage was found. Moreover, depending on the marker locus considered, linkage closer than or as close as the recombination frequency of 10-30% was excluded.

摘要

在六个大型父系家系（163 个信息丰富的雌性后代）中研究了布鲁拉基因座（Fec）与 11 个绵羊血液多态性基因座（即转铁蛋白（Tf）、血红蛋白（Hb）、碳酸酐酶（CA）、OLA 以及 A、B、C、D、M、R、F41 红细胞血型）之间的遗传连锁关系。所测试的六个父系对于布鲁拉等位基因（FecB）和几个遗传标记是杂合的。未发现支持连锁的证据。此外，根据所考虑的标记基因座，排除了重组频率低于或等于 10 - 30%的连锁关系。