Muti P
Divisione di Epidemiologia, Istituto dei Tumori, Milano.
Ann Ist Super Sanita. 1992;28(3):371-6.
Little experience is available to solve methodological and organizational problems when setting up a biological specimen bank as a support to prospective studies on chronic diseases. Sample aliquots preparation, processing procedures and storage system are discussed in the present paper. Problems related to the quality of biological material stored, as to the influence of the very low temperature freezing physico-chemical effects, are discussed also in the appendix.
在建立生物样本库以支持慢性病前瞻性研究时，解决方法学和组织问题的经验很少。本文讨论了样本分装制备、处理程序和存储系统。附录中还讨论了与所存储生物材料质量相关的问题，以及极低温度冷冻物理化学效应的影响。
