传染性肝炎病原体的研究。III. 传染性肝炎皮肤试验对封闭机构中该病发病率的影响。
Studies on the agent of infectious hepatitis. III. The effect of skin tests for infectious hepatitis on the incidence of the disease in a closed institution.
作者信息
DRAKE M E, WARD C, STOKES J, HENLE W, MEDAIRY G C, MANGOLD F, HENLE G
出版信息
J Exp Med. 1952 Mar;95(3):231-9. doi: 10.1084/jem.95.3.231.
At the onset of an epidemic in a closed institution about one-fourth of the inmates were skin-tested. During the year following the skin test, 5 cases of hepatitis with jaundice were recorded among 320 skin-tested individuals with unknown histories, one in the 144 skin test-positive, and 4 in the 176 skin test-negative subjects. In contrast 112 cases occurred among the 825 non-skin-tested individuals. Thus, the incidence of jaundice in the skin-tested group was 1.6 per cent as against 13.6 per cent in the non-skin-tested individuals. Possible explanations for this observation have been discussed.
在一个封闭机构中疫情爆发之初，约四分之一的 inmates 接受了皮肤测试。在皮肤测试后的一年里，在 320 名病史不明的接受皮肤测试者中记录到 5 例黄疸型肝炎病例，其中 1 例在 144 名皮肤测试呈阳性者中，4 例在 176 名皮肤测试呈阴性者中。相比之下，在 825 名未接受皮肤测试者中发生了 112 例。因此，接受皮肤测试组的黄疸发病率为 1.6%，而未接受皮肤测试者为 13.6%。已对这一观察结果的可能解释进行了讨论。
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