大鼠尿蛋白的电泳研究。
An electrophoretic study of urinary protein in the rat.
作者信息
SELLERS A L, ROBERTS S, RASK I, SMITH S, MARMORSTON J, GOODMAN H C
出版信息
J Exp Med. 1952 May 1;95(5):465-72. doi: 10.1084/jem.95.5.465.
Abstract
The nature of the proteins present in the urine of the normal rat has been investigated by electrophoretic analysis and by fractional precipitation of these proteins by ammonium sulfate. Components similar to serum alpha- and beta-globulin constitute the major portion of the urinary protein in both male and female rats. Following the intraperitoneal injection of renin, a massive proteinuria occurs. The proteins excreted are similar in proportion and electric mobility to those of normal rat serum.
摘要
通过电泳分析以及用硫酸铵对正常大鼠尿液中的蛋白质进行分级沉淀，对正常大鼠尿液中蛋白质的性质进行了研究。类似于血清α球蛋白和β球蛋白的成分构成了雄性和雌性大鼠尿蛋白的主要部分。腹腔注射肾素后，会出现大量蛋白尿。排泄出的蛋白质在比例和电泳迁移率方面与正常大鼠血清中的蛋白质相似。
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本文引用的文献
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Renin proteinuria in the rat; the relation between the proteinuria and the pressor effect of renin.大鼠肾素性蛋白尿；蛋白尿与肾素升压作用之间的关系。
J Exp Med. 1949 Feb;89(2):131-40. doi: 10.1084/jem.89.2.131.
2
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J Physiol. 1940 Jul 24;98(3):314-35. doi: 10.1113/jphysiol.1940.sp003852.
3
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