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[全身骨骼闪烁扫描在耳鼻喉科领域肿瘤分期中的重要性]

[Importance of whole body skeletal scintigraphy within the scope of staging of neoplasms in the ENT area].

作者信息

Piepenburg R, Bockisch A, Hach A, Steinert H, Welkoborsky H J, Kreuz S, Mann W J, Hahn K

机构信息

Klinik mit Poliklinik für Nuklearmedizin, Klinikum der Johannes Gutenberg-Universität Mainz.

出版信息

Laryngorhinootologie. 1992 Dec;71(12):605-10. doi: 10.1055/s-2007-997366.

Abstract

Concerning malignant tumours of the oral cavity, pharynx and larynx, bone metastases are in general rarely seen. For the specification to which patients the whole body bone scintigraphy as detection method should be applied, the findings of 370 patients were analysed retrospectively. In respect of primary staging, bone metastases could be found by scintigraphy in only 1.4% of the patients. On the other hand, there was a detection rate of 12% during the further course of the disease, especially in case of clinical symptoms pointing at spreading metastases or in tumour recurrences. Nevertheless, positive scan findings which were not due to metastases could be found in both groups with equal frequency (12 and 13%, respectively). Therefore the routine performance of whole body bone scintigraphy as a screening method does not seem to be useful in the primary staging of cancer of the mouth, pharynx and larynx. Contrary to this, in the follow-up of these tumours bone scanning proves to be a valuable and sensitive method for detecting skeletal metastases.

摘要

关于口腔、咽和喉的恶性肿瘤,骨转移通常很少见。为了明确作为检测方法的全身骨闪烁显像应应用于哪些患者,对370例患者的检查结果进行了回顾性分析。在初始分期方面,仅1.4%的患者通过闪烁显像发现骨转移。另一方面,在疾病的进一步发展过程中,检测率为12%,特别是在出现提示转移扩散的临床症状或肿瘤复发的情况下。然而,两组中发现非转移所致的阳性扫描结果的频率相同(分别为12%和13%)。因此,作为筛查方法的全身骨闪烁显像常规应用于口腔、咽和喉癌的初始分期似乎并无用处。与此相反,在这些肿瘤的随访中,骨扫描被证明是检测骨转移的一种有价值且敏感的方法。

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