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[儿童慢性复发性腮腺炎]

[Chronic recurrent parotitis in childhood].

作者信息

Grevers G

机构信息

Hals-Nasen-Ohrenklinik und Poliklinik der Ludwig-Maximilians-Universität München Klinikum.

出版信息

Laryngorhinootologie. 1992 Dec;71(12):649-52. doi: 10.1055/s-2007-997373.

Abstract

Juvenile recurrent parotitis (j.r.p.) is distinguished from the adult form by the course of the disease, therapeutic considerations and prognosis. Children suffering from j.r.p. are between 2 and 15 years of age; the male: female ratio is 1.5:1. In the present paper the author describes the different pathogenic theories of j.r.p. in accordance with the relevant literature. Besides malformation of the glandular duct like stenosis and ectasis, functional factors like the character of salivary secretion are suspected as being responsible for the disease. Other authors assume that a viral genesis, allergic factors, a physiological immaturity of the immune response, or family history may be the causes. In the evaluation of children with j.r.p. the patients' history with recurrent swelling episodes of the parotid gland(s) followed by quiescent periods is indicative. Further procedures like ultrasonography, sialography and MRI are discussed according to their diagnostic value. Therapeutic possibilities include antibiotics in the acute stage of the disease as well as parotidectomy in severe cases. Radiotherapy cannot be recommended because of its side effects (facial dysplasia, tumour induction). In most cases, the disease ends at puberty.

摘要

青少年复发性腮腺炎(j.r.p.)在病程、治疗考量及预后方面与成人型有所不同。患j.r.p.的儿童年龄在2至15岁之间,男女比例为1.5:1。在本文中,作者依据相关文献描述了j.r.p.的不同致病理论。除了腺管畸形如狭窄和扩张外,唾液分泌特性等功能因素也被怀疑与该病有关。其他作者认为病毒起源、过敏因素、免疫反应的生理不成熟或家族病史可能是病因。在评估患有j.r.p.的儿童时,腮腺反复肿胀发作后继而进入静止期的病史具有指示性。根据超声检查、唾液造影和磁共振成像等进一步检查的诊断价值进行了讨论。治疗方法包括在疾病急性期使用抗生素以及在严重病例中进行腮腺切除术。由于放疗的副作用(面部发育异常、诱发肿瘤),不建议采用放疗。在大多数情况下,该病在青春期结束。

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