Conrad M
Department of Computer Science, Wayne State University, Detroit, Michigan 48202.
Biosystems. 1992;27(4):223-33. doi: 10.1016/0303-2647(92)90061-3.
The activity of enzymes and other biological macromolecules is often sensitively dependent on physiochemical context. Seed germination provides an analogy that helps to elicit the control and information processing capabilities of enzymatic networks. Like a seed, the enzyme takes a particular action (complexes with a specific substrate and catalyzes a specific reaction) when a specific set of milieu influences is satisfied. The context sensitivity, specificity and speed are enormously enhanced by the parallelism inherent in the electronic wave function (i.e. by the superposition of electronic states). This parallelism is converted to speedup through electronic-conformational interactions. The quantum speedup effect allows biological 'switches' to have qualitatively greater pattern recognition capabilities than electronic switches. Consequently the information processing and control capabilities of biomolecular systems exceed the capabilities obtainable from classical models and exceed the intuitive expectations that have developed through the study of such models.
酶和其他生物大分子的活性通常对物理化学环境敏感地依赖。种子萌发提供了一个类比，有助于引出酶网络的控制和信息处理能力。就像种子一样，当满足特定的一组环境影响时，酶会采取特定的行动（与特定底物结合并催化特定反应）。电子波函数固有的并行性（即电子态的叠加）极大地增强了环境敏感性、特异性和速度。这种并行性通过电子 - 构象相互作用转化为加速。量子加速效应使生物“开关”具有比电子开关在定性上更强的模式识别能力。因此，生物分子系统的信息处理和控制能力超过了经典模型所能获得的能力，也超出了通过对这类模型的研究而形成的直观预期。
