Hohenberger W, Thom N, Hermanek P, Gall F P
Klinik und Poliklinik für Chirurgie, Universität Regensburg.
Langenbecks Arch Chir Suppl Kongressbd. 1992:83-8.
Even rectal carcinomas, carcinomas of the female genital tract, and retroperitoneal sarcomas of the pelvis with invasion of adjacent organs are potentially curable by extending the operation to the relevant structures. In the Surgical Department of the University of Erlangen, 1535 patients with a first diagnosis of rectal carcinoma were treated from 1978 to 1988. Among these patients, 97 multivisceral pelvic resections (patients with distant metastases excluded) were performed. True tumor invasion had occurred in 48%, the others were operated on for inflammatory adhesion. In 54 patients, the anal sphincter was preserved. Postoperative mortality was 7%. The 5-year survival of those patients with tumor invasion of adjacent organs and R0-resection (n = 26) was 32%. Excluding the five patients with a tear or incision of the tumor (n = 5), the 5-year survival of the remaining patients was 44%. One patient who was operated on for a leiomyosarcoma of the rectum with a multivisceral resection of the rectum, prostate, and urine bladder is still alive 9 years after the operation without recurrence. The history of this patient argues for pelvic exenteration also in males, if a R0 resection can be performed.
即使是直肠癌、女性生殖道癌以及侵犯相邻器官的盆腔腹膜后肉瘤,通过将手术范围扩大至相关结构也有可能治愈。1978年至1988年期间,埃尔朗根大学外科收治了1535例初诊为直肠癌的患者。其中,进行了97例多脏器盆腔切除术(排除远处转移患者)。48%的患者存在真正的肿瘤侵犯,其他患者因炎性粘连接受手术。54例患者保留了肛门括约肌。术后死亡率为7%。肿瘤侵犯相邻器官且行R0切除的患者(n = 26)5年生存率为32%。排除肿瘤破裂或切开的5例患者(n = 5),其余患者的5年生存率为44%。1例因直肠平滑肌肉瘤接受直肠、前列腺和膀胱多脏器切除手术的患者,术后9年仍存活且无复发。该患者的病史表明,如果能进行R0切除,男性患者也可考虑行盆腔脏器清除术。