Misaki T, Koh T, Shimbo S, Kasagi K, Konishi J
Department of Nuclear Medicine, Kyoto University School of Medicine, Japan.
Thyroid. 1992 Winter;2(4):325-7. doi: 10.1089/thy.1992.2.325.
We found familial thyroid ectopy in a mother and son, each of whom had an anterior neck mass corresponding to a perihyoid ectopic thyroid. In addition, technetium scintigraphy revealed another focus of aberrant uptake at their tongue roots. Neither patient showed hypothyroid symptoms or abnormal biochemical data other than a mildly elevated TSH level in the son. No other member of the family had a thyroid disorder. To our knowledge this is the first documented instance of familial thyroid ectopy in multiple sites. The observed similarity in distribution of ectopic tissue suggests a hereditary pathogenic factor.
我们在一位母亲和她儿子身上发现了家族性甲状腺异位，他们每个人的颈部前方都有一个肿块，对应舌骨周围的异位甲状腺。此外，锝闪烁扫描显示他们舌根处还有另一个异常摄取点。除了儿子的促甲状腺激素水平轻度升高外，两位患者均未表现出甲状腺功能减退症状或异常生化数据。家族中没有其他成员患有甲状腺疾病。据我们所知，这是首例记录在案的多部位家族性甲状腺异位病例。观察到的异位组织分布相似性提示存在遗传致病因素。
