Deitmer T
Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Westfälischen Wilhelms-Universität Münster.
HNO. 1992 Dec;40(12):459-63.
This review article deals with current understanding of mucociliary transport and its significance for clinical practice. The ultrastructure of cilia and principles of mucociliary clearance in the upper respiratory tract are outlined. Practicable diagnostic measures described are the saccharine test, vital cytological sampling of the nasal mucosa and electron microscopy for ultrastructural studies. Special pathologies such as the immotile cilia syndrome and mucoviscidosis are outlined in their relation to mucociliary transport. Recommendations are given as to how mucociliary transport might be influenced therapeutically.
这篇综述文章探讨了目前对黏液纤毛运输的理解及其在临床实践中的意义。概述了上呼吸道纤毛的超微结构和黏液纤毛清除的原理。所描述的可行诊断方法包括糖精试验、鼻黏膜活体细胞学采样以及用于超微结构研究的电子显微镜检查。诸如纤毛不动综合征和黏液黏稠症等特殊病理学情况与黏液纤毛运输的关系也作了概述。文中还给出了关于如何从治疗上影响黏液纤毛运输的建议。
