Koizuka M, Kuwajima I, Suzuki Y, Matsushita S, Kuramoto K
Division of Cardiology, Tokyo Metropolitan Geriatric Hospital.
Nihon Ronen Igakkai Zasshi. 1992 Dec;29(12):912-7. doi: 10.3143/geriatrics.29.912.
Changes in blood pressure (BP) and pulse rate were measured during visits to a doctor's office by means of an non-invasive ambulatory BP monitoring device in 47 elderly hypertensive patients (mean age 73.0 years). Systolic BP increased from 140.5/85.4 mmHg to 157.9/85.7 mmHg immediately after entering the doctor's office and tended to return to the previous level at 5 minutes after entering although diastolic BP did not change during the visit. Pulse rate also increased slightly, but significantly on entering the office. The difference in BP between 25 minute before and just after entering an office was +17.4 mmHg in systolic. -0.1 mmHg in diastolic. If an increment in systolic BP more than 10 mmHg was defined as positive for white coat effect, they were observed in 59.6%. The frequency of white coat hypertension was 46.7% in the age of sixties, 65.2% in seventies and 66.7% in eighties but there was no significant difference among 3 groups. There was a tendency for white coat hypertensions to be more frequent in men compared than in women (p = 0.07).
47例老年高血压患者（平均年龄73.0岁）在前往医生办公室就诊期间，使用无创动态血压监测设备测量血压（BP）和脉搏率变化。进入医生办公室后，收缩压立即从140.5/85.4 mmHg升至157.9/85.7 mmHg，进入办公室5分钟后虽舒张压在就诊期间未变化，但收缩压有回到先前水平的趋势。脉搏率也略有增加，但进入办公室时显著增加。进入办公室前25分钟与刚进入办公室后的血压差值，收缩压为+17.4 mmHg，舒张压为-0.1 mmHg。若将收缩压升高超过10 mmHg定义为白大衣效应阳性，则有59.6%的患者出现该效应。白大衣高血压的发生率在60多岁患者中为46.7%，70多岁患者中为65.2%，80多岁患者中为66.7%，但三组之间无显著差异。男性白大衣高血压的发生率有高于女性的趋势（p = 0.07）。
