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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Aziz S, Hasnain S N, Zain B K

Z Naturforsch C Biosci. 1978 Jan-Feb;33(1-2):70-2. doi: 10.1515/znc-1978-1-213.

Liver and serum aspartate aminotransferase (GOT) and alanine aminotransferase (GPT) activities were measured in a hibernating desert lizard, Uromastix hardwickii. The levels of both enzymes were found to be lower in hibernation than during the active period, particularly in the liver. 2. After intramuscular injection of 2 mg of cortisone acetate there was a rapid rise in the levels of these enzymes with a peak of 18 hours (GOT) and 12 hours (GPT). 3. The response of both enzymes to cortisone was much greater during the active period than during hibernation. 4. GOT showed a much more rapid and greater response to cortisone than GPT. This is in contrast to the response of rat liver where GPT is more responsive to this hormone. 5. These studies indicate that the transferase enzymes of this lizard differ from those of the rat in their sensitivity and time of response to cortisone.

对一种冬眠的沙漠蜥蜴——硬尾沙蜥的肝脏和血清中的天冬氨酸转氨酶（GOT）和丙氨酸转氨酶（GPT）活性进行了测定。发现这两种酶的水平在冬眠时比活跃期低，尤其是在肝脏中。2. 肌肉注射2毫克醋酸可的松后，这些酶的水平迅速上升，GOT在18小时达到峰值，GPT在12小时达到峰值。3. 这两种酶在活跃期对可的松的反应比冬眠时大得多。4. GOT对可的松的反应比GPT更快、更大。这与大鼠肝脏的反应相反，在大鼠肝脏中GPT对这种激素更敏感。5. 这些研究表明，这种蜥蜴的转氨酶在对可的松的敏感性和反应时间上与大鼠的不同。

Aziz S, Hasnain S N, Zain B K

Z Naturforsch C Biosci. 1978 Jan-Feb;33(1-2):70-2. doi: 10.1515/znc-1978-1-213.

Liver and serum aspartate aminotransferase (GOT) and alanine aminotransferase (GPT) activities were measured in a hibernating desert lizard, Uromastix hardwickii. The levels of both enzymes were found to be lower in hibernation than during the active period, particularly in the liver. 2. After intramuscular injection of 2 mg of cortisone acetate there was a rapid rise in the levels of these enzymes with a peak of 18 hours (GOT) and 12 hours (GPT). 3. The response of both enzymes to cortisone was much greater during the active period than during hibernation. 4. GOT showed a much more rapid and greater response to cortisone than GPT. This is in contrast to the response of rat liver where GPT is more responsive to this hormone. 5. These studies indicate that the transferase enzymes of this lizard differ from those of the rat in their sensitivity and time of response to cortisone.

对一种冬眠的沙漠蜥蜴——硬尾沙蜥的肝脏和血清中的天冬氨酸转氨酶（GOT）和丙氨酸转氨酶（GPT）活性进行了测定。发现这两种酶的水平在冬眠时比活跃期低，尤其是在肝脏中。2. 肌肉注射2毫克醋酸可的松后，这些酶的水平迅速上升，GOT在18小时达到峰值，GPT在12小时达到峰值。3. 这两种酶在活跃期对可的松的反应比冬眠时大得多。4. GOT对可的松的反应比GPT更快、更大。这与大鼠肝脏的反应相反，在大鼠肝脏中GPT对这种激素更敏感。5. 这些研究表明，这种蜥蜴的转氨酶在对可的松的敏感性和反应时间上与大鼠的不同。