Duché B, Marchal C, Loiseau P, Louvet-Giendaj C
Service de Neurologie, Hôpital Pellegrin, Bordeaux.
Rev Neurol (Paris). 1992;148(8-9):562-5.
Neuronal migration anomalies are caused by insults occurring during the third to fifth gestational months when neuroblasts migrate from the germinal zone to the cortical plate. They lead to several cerebral malformations such as macrogyria, identified nowadays by MRI. We describe a case of bilateral parieto-rolandic macrogyria responsible for a bi-opercular syndrome resulting in a facio-linguo-masticatory diplegia associated with mental retardation and severe epilepsy.
神经元迁移异常是由妊娠第三个月至第五个月期间发生的损伤引起的,此时神经母细胞从生发区迁移至皮质板。它们会导致几种脑畸形,如巨脑回,如今可通过磁共振成像(MRI)识别。我们描述了一例双侧顶枕颞叶巨脑回病例,其导致双颞叶综合征,进而引发面舌咀嚼性双侧瘫痪,并伴有智力障碍和严重癫痫。