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[通过对鸟类粪便和食肉哺乳动物排泄物进行血清学检测探索亚美尼亚土拉菌病和鼠疫的自然疫源地]

[Exploration of natural foci of tularemia and plague in Armenia using the serological examination of bird droppings and excrements of predatory mammals].

作者信息

Dobrokhotov B P, Mnatsakanian A G, Meshcheriakova I S, Rudnev M M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Feb(2):111-5.

PMID:149478
Abstract

Forty strains of tularemia and 619 of plague microbes were isolated in 1974 in bacteriological examination of natural plague and tularemia foci from a great number of small mammals and their ectoparasites. At the same time in serological examination (in the antibody neutralization test) of bird pellets, 52 mummified cadavers, and 34 excretion samples of mammalian beasts of prey collected in Armenia (its central and North-Western part) in 1973 the antigen of tularemia microbe was revealed in 73, 8, and 3, and of plagye--in 42, 5, and 1 cases, respectively. In one of the sites examined the number of positive findings failed to exceed 10--17%, this indicating a low intensity of the epizootic in the majority of the places. Judging by the mean titres of the serological test, which varied from 1:12 to 1:1428 in examination for tularemia and from 1:12 to 1428 in examination for plague, it was possible to detect both epizootics coursing during the examination, and those which occurred several monts ago. Tularemia and plague foci were not infrequently present at the same territories, and these diseases could involve the same individual animals of Microtus arvalis (Pall.). The data obtained pointed to the greater effectiveness of examination of bird's pellets and excretions of mammalian beasts of prey for the reconnaisance investigation of the natural foci of plague and tularemia in comparison with the bacteriological methods applied usually.

摘要

1974年,在对大量小型哺乳动物及其体外寄生虫进行的自然鼠疫和土拉菌病疫源地细菌学检查中,分离出40株土拉菌和619株鼠疫杆菌。同时,在对1973年在亚美尼亚(中部和西北部)采集的鸟类粪便、52具木乃伊化尸体以及34份哺乳动物食肉动物排泄物样本进行血清学检查(抗体中和试验)时,分别在73份、8份和3份样本中检测出土拉菌抗原,在42份、5份和1份样本中检测出鼠疫抗原。在所检查的一个地点,阳性结果数量未超过10% - 17%,这表明大多数地方的动物流行病强度较低。从血清学检测的平均滴度来看,土拉菌病检测的滴度范围为1:12至1:1428,鼠疫检测的滴度范围为1:12至1428,据此不仅可以检测出检查期间正在发生的动物流行病,还能检测出几个月前发生的流行病。土拉菌病和鼠疫疫源地常常出现在同一地区,而且这些疾病可能感染同一只田鼠(Pall.)。所获得的数据表明,与通常采用的细菌学方法相比,检查鸟类粪便和哺乳动物食肉动物排泄物对于鼠疫和土拉菌病自然疫源地的侦察调查更有效。

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