Boucek C, Klain M, Obuchowski N, Molner R
Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh School of Medicine, PA.
J Clin Monit. 1992 Jul;8(3):209-15. doi: 10.1007/BF01616778.
The effect of pulmonary artery (PA) catheter insertion on cardiac output measurements and the effect of single-lung ventilation on data derived from catheters placed in both the right and left pulmonary arteries were examined in 17 anesthetized mongrel dogs. Serial tricarboncyanine dye measurements of cardiac output were taken at baseline and after insertion of each of two PA catheters, one catheter in each lung, to detect possible changes in cardiac output due to instrumentation. In the second part of the study, single-lung ventilation was achieved through a Kottmeier double-lumen tube. Right and left paired values of thermodilution cardiac output, PA systolic pressure, and PA PO2 were compared during ventilation of both lungs, during right lung ventilation, during return to ventilation of both lungs, and during left lung ventilation. Mean dye-dilution cardiac outputs were not significantly different after one or two catheters were inserted. Paired right and left values were similar for thermodilution cardiac output, PA PO2, and pulmonary systolic pressure, regardless of ventilation conditions. Even during single-lung ventilation, data obtained from PA catheters in the ipsilateral and contralateral lung were equivalent in supine dogs.
在17只麻醉的杂种犬中，研究了肺动脉（PA）导管插入对心输出量测量的影响，以及单肺通气对置于左右肺动脉的导管所获取数据的影响。在基线时以及插入两根PA导管（每侧肺各一根）中的每一根之后，连续采用三氰化染料测量心输出量，以检测因器械操作导致的心输出量可能发生的变化。在研究的第二部分，通过Kottmeier双腔管实现单肺通气。比较双肺通气期间、右肺通气期间、恢复双肺通气期间以及左肺通气期间热稀释心输出量、PA收缩压和PA PO2的左右配对值。插入一根或两根导管后，平均染料稀释心输出量无显著差异。无论通气条件如何，热稀释心输出量、PA PO2和肺收缩压的左右配对值相似。即使在单肺通气期间，仰卧位犬同侧和对侧肺的PA导管所获取的数据也是等效的。
