SCHWERDT C E, PARDEE A B
J Exp Med. 1952 Aug;96(2):121-36. doi: 10.1084/jem.96.2.121.
A procedure has been described for the centrifugal fractionation of the cellular particulate components of CNS tissue infected with poliomyelitis virus. A study of the distribution of infectivity among these components revealed that approximately four-fifths of the virus is found free in the submicroscopic particle fraction. The validity of the conclusion that the virus is located in this fraction of the intact neuron is discussed.
已经描述了一种用于对感染脊髓灰质炎病毒的中枢神经系统组织的细胞颗粒成分进行离心分级分离的方法。对这些成分中感染性分布的研究表明，大约五分之四的病毒存在于亚微观颗粒部分的游离状态。讨论了关于病毒位于完整神经元的这一部分中的结论的有效性。
